Evaluación longitudinal de la mucositis oral en el trasplante de células madre hematopoyéticas: un estudio piloto

Carolina Eurich Mazur; Camila Pinheiro Furquim; Samir Kanaan Nabhan; Geisla Mary Silva Soares; José Miguel Amenábar; Cassius Carvalho Torres-Pereira

doi:10.59334/ROV.v1i30.132

Autores/as

Carolina Eurich Mazur Federal University of Parana.
Camila Pinheiro Furquim Federal University of Parana.
Samir Kanaan Nabhan Federal University of Parana.
Geisla Mary Silva Soares Federal University of Parana.
José Miguel Amenábar Federal University of Parana.
Cassius Carvalho Torres-Pereira Federal University of Parana.

DOI:

https://doi.org/10.59334/ROV.v1i30.132

Palabras clave:

Mucositis Oral, Trasplante de células madre, Neoplasmas hematológicos

Resumen

Objetivo: describir la incidencia y el puntaje de la mucositis oral (MO) y las morbilidades relacionadas en individuos sometidos a trasplante de células madre hematopoyéticas (TCMH) a lo largo del período de inmunosupresión.

Métodos: Los sujetos con enfermedades onco / hematológicas, mayores de 14 años, sometidos a TCMH alogénico fueron evaluados diariamente por la presencia y clasificación de OM, nivel de dolor, disfagia, disgeusia y xerostomía. El examen comenzó dos días antes de la infusión de células madre hematopoyéticas y finalizó veinte días después. La OM se clasificó de acuerdo con la escala de la OMS y se utilizó la escala analógica visual (EVA) para medir el nivel de dolor.

Resultados: se reclutaron 23 individuos, el 83% con enfermedades malignas y el 91% con OM. La mediana del grado máximo de OM fue 3 y el nivel máximo de dolor fue 9. Hubo una mediana de 11 días de uso de medicación opioide. Los sujetos que tuvieron el mayor número de días con dolor en la boca alcanzaron el grado máximo de OM y el mayor número de días y el uso de opioides.

Conclusión: Hubo una alta incidencia y puntuaciones más altas de OM, pérdida de masa corporal y dolor en esta muestra.

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Citas

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