Influencia de la periodontitis en el carcinoma oral de células escamosas: revisión narrativa

Autores/as

  • Jorge Briceño Universidad Andrés Bello, Chile.
  • Daniela Cavagnola Universidad Andrés Bello, Chile.
  • Jorge Candia Universidad Andrés Bello, Chile.
  • Carolina Somarriva Universidad Andrés Bello, Chile.
  • Alejandra Fernández Universidad Andrés Bello, Chile.

DOI:

https://doi.org/10.59334/ROV.v2i29.151

Palabras clave:

Cáncer oral, cavidad oral, periodontitis

Resumen

El carcinoma oral de células escamosas (COCE) es el tipo de cáncer más frecuente en la cavidad oral, y constituye el 95% de la totalidad de neoplasias malignas a escala bucal. La etiología de COCE es multifactorial y su patogenia se ha asociado, entre otros, a los cambios que acontecen en su microambiente. La inflamación que invade el microambiente de COCE se ha relacionado con la invasión, progresión, carácter fuerte y pronóstico de COCE. Es por tal motivo, que la periodontitis, inflamación del tejido periodontal, de alta prevalencia en la población adulta, se ha relacionado con COCE. Al respecto, estudios clínicos advirtieron que la periodontitis representa un riesgo para desarrollar COCE y estudios in vitro, puntualizaron que la periodontitis favorece la tumorogenicidad y lo combativo de COCE. El objetivo de la siguiente revisión narrativa es describir los efectos de la periodontitis en el comportamiento del carcinoma oral de células escamosas.

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Citas

Ahn, J., Segers, S., Hayes, R. (2007). Periodontal disease, Porphyromonas gingivalis serum antibody levels and oro-digestive cancer mortality. Carcinogenesis,33(5), 1055-1058. https://doi.org/10.1093/carcin/bgs112

Azimi, H.; Khajehahmadi, S.; Rahpeyma, A. (2014). Tongue Squamous Cell Carcinoma: A Clinical Study. Iran J Pathol., 9(1), 28–32.

Binder, Gallimidi, A., Fischman, S., Revach, B.; Bulvik, R., Maliutina, A., Rubinstein, AM, Nussbaum, G., Elkin, M. (2015). Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor pro-gression in an oral-specific chemical carcinogenesis model. Oncotarget., 6(26), 22613-22623. https://doi.org/10.18632/oncotarget.4209

Bonde, A.K., Tischler, V., Kumar, S., Soltermann, A., Schwendener, R.A. (2012). Intratumoral macrophages contri-bute to epithelial-mesenchymal transition in solid tumors. BMC Cancer, 12:35. https://doi.org/10.1186/1471-2407-12-35

Chang, J.S., Lo, H.I.; Wong, T.Y., Huang, C.C., Lee, W.T., Tsai, S.T., Chen, K.C., Yen, C.J., Wu, Y.H., Hsueh, W.T., Yang, M.W., Wu, S.Y., Chang, K.Y., Chang, J.Y., Ou, C.Y., Wang, Y.H., Weng, Y.L., Yang, H.C., Wang, F.T., Lin, C.L., Huang, J.S., Hsiao, J.R., (2013). Investigating the association between oral hygiene and head and neck cancer. Oral Oncol., 49(10), 1010-7. https://doi.org/10.1016/j.oraloncology.2013.07.004

Costa, N., Valadares, M., Souza, P., Mendonça, E., Oliveira, J., Silva, T.A., Batista, A. (2013). Tumor-associated ma-crophages and the profile of inflammatory cytokines in oral squamous cell carcinoma. Oral Oncol.,49(3), 216-23. https://doi.org/10.1016/j.oraloncology.2012.09.012

De Lima, P.O., Dos Santos, F.V., Oliveira, D.T., De Figueiredo, R.C., Pereira, M.C. (2015). Effect of eosinophil cationic protein on human oral squamous carcinoma cell viability. Mol Clin Oncol., 3(2), 353-356. https://doi.org/10.3892/mco.2014.477

Divaris, K., Olshan, A.F., Smith, J., Bell, M.E., Weissler, M.C., Funkhouser, W.K., Bradshaw, P.T. (2010). Oral health and risk for head and neck squamous cell carcinoma: the Carolina Head and Neck Cancer Study. Cancer Causes Control, 21(4), 567-75. https://doi.org/10.1007/s10552-009-9486-9

Eke, P.I., Zhang, X., Lu, H., Wei, L., Thornton-Evans, G., Greenlund, K.J., Holt, J.B., Croft, J.B. (2016). Predicting Pe-riodontitis at State and Local Levels in the United States. J Dent Res., 95(5), 515-22. https://doi.org/10.1177/0022034516629112

Fernández, A., Córdova, P., Badenier, O., Esguep, A. (2015). Epidemiological characterization of oral cancer. Litera-ture review. J Oral Res., 4(2), 137–45. https://doi.org/10.17126/joralres.2015.027

Galvão-Moreira, L.V., & Da Cruz, M.C. (2016). Oral microbiome, periodontitis and risk of head and neck cancer. Oral Oncol., 53, 17-9. https://doi.org/10.1016/j.oraloncology.2015.11.013

Gholizadeha, P., Eslamib, H.; Yousefic, M., Asgharzadehd, M., Mohammad Aghazadehe, M., Kafil, H.S. (2016). Role of oral microbiome on oral cancers, a review. Biomed Pharmacother., 8, 552–558. https://doi.org/10.1016/j.biopha.2016.09.082

Glogauer, J., Sun, C., Bradley, G., Magalhaes, M. (2015). Neutrophils Increase Oral Squamous Cell Carcinoma Inva-sion through an Invadopodia-Dependent Pathway. Cancer Immunol Res., 3(11), 1218-1226. https://doi.org/10.1158/2326-6066.CIR-15-0017

Gondivkar, S.M., Gondivkar, R.S., Gadbail, A.R., Chole, R., Mankar, M., Yuwanati, M. (2013). Chronic periodontitis and the risk of head and neck squamous cell carcinoma: facts and figures. Exp Oncol., 35(3), 163-7.

Gupta, B., Johnson, W.W., Kumar, N. (2016). Global Epidemiology of Head and Neck Cancers: A Continuing Cha-llenge. Oncology., 91(1), 13-23. https://doi.org/10.1159/000446117

Ha, N.H., Woo, B.H., Kim, D.J., Ha, E.S., Choi, J.I., Kim, S.J., Park, B.S., Lee, J.H., Park, H.R. (2015). Prolonged and repetitive exposure to Porphyromonas gingivalis increases aggressiveness of oral cancer cells by promoting acqui-sition of cancer stem cell properties. Tumour Biol., 36(12), 9947-60. https://doi.org/10.1007/s13277-015-3764-9

Ha, N., Park, D., Woo, B., Kim, D., Choi, J., Park, B., Kim, Y., Lee, J., Park, H. (2016). Porphyromonas gingivalis in-creases the invasiveness of oral cancer cells by upregulating IL-8 and MMPs. Cytokine, 86, 64-72. https://doi.org/10.1016/j.cyto.2016.07.013

Ha, N.H., Park, D.G., Woo, B.H., Kim Da, J., Choi, J.I., Park, B.S., Kim, Y.D., Lee, J.H., Park, H.R. (2016). Porphyromo-nas gingivalis increases the invasiveness of oral cancer cells by upregulating IL-8 and MMPs. Cytokine., 86, 64-72. https://doi.org/10.1016/j.cyto.2016.07.013

Hu, Y., He, M.Y., Zhu, L.F., Yang, C.C., Zhou, M.L., Wang, Q., Zhang, W., Zheng, Y.Y., Wang, D.M., Xu, Z.Q., Wu, Y.N., Liu, L.K. (2016). Tumor-associated macrophages correlate with the clinicopathological features and poor outco-mes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma. J Exp Clin Cancer Res., 35:12. https://doi.org/10.1186/s13046-015-0281-z

Inaba, H., Sugita, H., Kuboniwa, M., Iwai, S., Hamada, M., Noda, T., Morisaki, I., Lamont, R., Amano, A. (2014). Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation. Cell Microbiol.,16(1), 131-45. https://doi.org/10.1111/cmi.12211

Jain, M., Kasetty, S., Sudheendra, U.S., Tijare, M., Khan, S., Desai, A. (2014). Assessment of tissue eosinophilia as a prognosticator in oral epithelial dysplasia and oral squamous cell carcinoma-an image analysis study. Patholog Res Int., Vol 2014 (2014), 507-512. https://doi.org/10.1155/2014/507512

Krüger, M., Hansen, T., Kasaj. A., Moergel. M. (2013). The Correlation between Chronic Periodontitis and Oral Can-cer, Case Reports in Dentistry, vol. 2013. https://doi.org/10.1155/2013/262410

Lao, X.M., Liang, Y.J., Su, Y.X., Zhang, S.E., Zhou, X.I., Liao, G.Q. (2016). Distribution and significance of interstitial fibrosis and stroma-infiltrating B cells in tongue squamous cell carcinoma. Oncol Lett., 11(3), 2027-2034. https://doi.org/10.3892/ol.2016.4184

Missih C. (2013). The link between periodontal disease and cancer: A review. Perioimplantadvisory, 2013.

Moergel, M., Kämmerer, P., Kasaj, A., Armouti, E., Alshihri, A., Weyer, V., Al-Nawas, B. (2013). Chronic periodontitis and its possible association with oral squamous cell carcinoma - a retrospective case control study. Head Face Med., 9:39. https://doi.org/10.1186/1746-160X-9-39

Moraes, R.C., Dias, F.L., Figueredo, C.M., Fischer, R.G. (2016). Association between Chronic Periodontitis and Oral/ Oropharyngeal Cancer. Braz Dent J., 27(3), 261-6. https://doi.org/10.1590/0103-6440201600754

Mori, K., Hiroi, M., Shimada, J., Ohmori, Y. (2011). Infiltration of m2 tumor-associated macrophages in oral squa-mous cell carcinoma correlates with tumor malignancy. Cancers (Basel)., 3(4), 3726-39. https://doi.org/10.3390/cancers3043726

Quan, H., Fang, L., Pan, H., Deng, Z., Gao, S., Liu, O., Wang, Y., Hu, Y, Fang, X., Yao, Z., Guo, F., Lu, R., Xia, K., Tang, Z. (2016). An adaptive immune response driven by mature, antigen-experienced T and B cells within the microen-vironment of oral squamous cell carcinoma. Int J Cancer., 138(12), 2952-62. https://doi.org/10.1002/ijc.30019

Rhodus, N.L., Kerr, A.R., Patel, K. (2014). Oral cancer: leukoplakia, premalignancy, and squamous cell carcinoma. Dent Clin North Am., 58(2), 315–40. https://doi.org/10.1016/j.cden.2013.12.004

Seppälä, M., Tervo, S., Pohjola, K., Laranne, J., Huhtala, H., Toppila-Salmi, S., Paavonen, T. (2015). The association and prognostic relevance of cancerous inhibitor of protein phosphatase 2A and inflammation in tongue squa-mous cell carcinoma. APMIS., 123(12), 1007-15. https://doi.org/10.1111/apm.12462

Silva, N., Abusleme, L., Bravo, D., Dutzan, N., Garcia-Sesnich, J., Vernal, R.; Hernández M., Gamonal, J. (2015). Host response mechanisms in periodontal diseases. J Appl Oral Sci., 23(3), 329-55. https://doi.org/10.1590/1678-775720140259

Wen, B.W., Tsai, C.S.; Lin, C.L., Chang, Y.J., Lee, C.F., Hsu, C.H., Kao, C.H. (2014). Cancer risk among gingivitis and periodontitis patients: a nationwide cohort study. QJM., 107(4), 283-90. https://doi.org/10.1093/qjmed/hct248

Zeng, X.T., Leng, W.D., Zhang, C., Liu, J., Cao, S.Y., Huang, W. (2015). Meta-analysis on the association between toothbrushing and head and neck cancer. Oral Oncol., 51(5), 446-51. https://doi.org/10.1016/j.oraloncology.2015.02.095

Zhou, X.; Su, Y.; Lao, X.; Liang, Y., Liao, G. (2016). CD19+IL-10+ regulatory B cells affect survival of tongue squa-mous cell carcinoma patients and induce resting CD4+ T cells to CD4+Foxp3+ regulatory T cells. Oral Oncology., 5327-35. https://doi.org/10.1016/j.oraloncology.2015.11.003

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Publicado

2018-12-01

Cómo citar

Briceño, J., Cavagnola, D., Candia, J., Somarriva, C., & Fernández, A. (2018). Influencia de la periodontitis en el carcinoma oral de células escamosas: revisión narrativa. O.V., 2(29), 70–77. https://doi.org/10.59334/ROV.v2i29.151

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Artículo de investigación

Métricas alternativas