Cambios en la composición salival de personas químicamente dependientes.

Luciana Lyra; William Bellani; Carolina E. Mazur; João A. Brancher; Antonio Adilson S. de Lima; José Miguel Amenábar

doi:10.59334/ROV.v1i32.381

Autores/as

Luciana Lyra Universidade Federal do Paraná
William Bellani Universidade Federal do Paraná
Carolina E. Mazur Universidade Federal do Paraná
João A. Brancher Pontifícia Universidade Católica do Paraná
Antonio Adilson S. de Lima Universidade Federal do Paraná
José Miguel Amenábar Universidade Federal do Paraná

DOI:

https://doi.org/10.59334/ROV.v1i32.381

Palabras clave:

Saliva, alcohol, cannabis, cocaína, composición salival, desórdenes asociados a sustancias, dependencia a sustancias, drogas

Resumen

Los dependientes químicos pueden presentar cambios relevantes en el volumen y la composición de la saliva, debido a que la secreción de las glándulas salivales es controlada por el sistema parasimpático y simpático. El objetivo de este estudio fue comparar la concentración salival de proteínas totales, amilasa, urea, calcio, fosfato y la velocidad de flujo salival entre personas con dependencia química y no dependientes. Cada grupo fue formado por 27 participantes. La velocidad del flujo salival y las concentraciones de calcio, fosfato, proteína total, amilasa y urea se midieron en ambos grupos. Las muestras de saliva de los dependientes químicos se tomaron un día antes de comenzar el tratamiento de desintoxicación. El análisis estadístico se realizó por medio del test t de student.

El flujo salival y la concentración de urea no presentaron diferencias estadísticamente significativas entre los grupos. Sin embargo, las concentraciones de proteínas totales, amilasa, calcio y fosfato fueron estadísticamente mayores en el grupo de dependientes químicos. El uso crónico de alcohol y de drogas ilícitas provocan modificaciones en la composición salival.

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