Visión celular y molecular de la ortopedia funcional de los maxilares

Elías Ernesto Aguirre Siancas; Silvia Granados Martínez

doi:10.59334/ROV.v1i26.225

Autores/as

Elías Ernesto Aguirre Siancas Universidad Nacional Mayor de San Marcos, Perú.
Silvia Granados Martínez Universidad Nacional Federico Villarreal, Perú.

DOI:

https://doi.org/10.59334/ROV.v1i26.225

Palabras clave:

Estimulación ortopédica funcional, osteocitos, mecanotransducción, uniones comunicantes

Resumen

Actualmente, los mecanismos biológicos que subyacen a la estimulación ortopédica funcional están en proceso de entendimiento; sin embargo, se sabe que el osteocito juega un rol esencial, al recibir y transformar dicho estímulo funcional hacia una señal bioquímica, lo que da como consecuencia la secreción de diversas moléculas. Estas se movilizan entre los osteocitos, gracias a su extensa red de uniones comunicantes, y llegan en última instancia a activar a las células efectoras del tejido óseo: osteoblastos y osteoclastos. El objetivo de la revisión es actualizar y compendiar algunos de los más importantes mecanismos celulares y moleculares subyacentes a la terapia ortopédica funcional de los maxilares.

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