Intraosseous mucoepidermoid carcinoma in mandible: Case report and literature review

Authors

  • Sandro Alexander Lévano Loayza Cayetano Heredia Peruvian University
  • Alfredo Yupanqui Pellanne Cayetano Heredia Peruvian University

DOI:

https://doi.org/10.59334/ROV.v1i34.429

Keywords:

Mucoepidermoid carcinoma, mandible, salivary glands, oral pathology, diagnosis,, mouth neoplasms

Abstract

Introduction: Intraosseous mucoepidermoid carcinoma is a very rare malignant neoplasm of the salivary glands, it has the ability to develop in any part of the mouth, being the molar premolar area and mandibular angle the most frequent sites of its finding.

Objective: To report the case of a low grade intraosseous mucoepidermoid carcinoma in the jaw, in an older adult patient who was diagnosed in an Oral and Maxillofacial Surgery Service after being referred by a general private dentist.

Methods: A clinical examination was carried out and indicated the taking of panoramic radiography, tomography and incisional biopsy.

Results: The biopsy resulted in intraosseous mucoepidermoid carcinoma and was later transferred to the Oncology Service.

Conclusion: Intraosseous mucoepidermoid carcinoma is an infrequent pathology, with a favorable prognosis when it is detected early and has similar characteristics to other not so aggressive pathologies.

Downloads

Download data is not yet available.

References

Alexander RW, Dupuis RH, Holton H. Central mucoepidermoid tumor (carcinoma) of the mandible. J Oral Surg. 1974;32:541–7.

Basaran, B.; Doruk, C.; Yılmaz, E.; Sünnetçio lu, E.; Bilgiç, B. Intraosseous mucoepidermoid carcinoma of the jaw: report of three cases. Turk Arch Otorhinolaryngol, 56(1):42-6, 2018. https://doi.org/10.5152/tao.2018.2902

Bell, D.; Lewis, C.; El-Naggar, A. K.; & Weber, R. S. Primary intraosseous mucoepidermoid carcinoma of the jaw: Reappraisal of The MD Anderson Cancer Center experience. Head & Neck, 38(S1), E1312–17, 2015. https://doi.org/10.1002/hed.24219

Bishop, J. A.; Yonescu, R.; Batista, D.; Yemelyanova, A.; Ha, P. K.; & Westra, W. H. Mucoepidermoid carcinoma does not harbor transcriptionally active high risk human papillomavirus even in the absence of the MAML2 translocation. Head and Neck Pathology, 8(3), 298–302, 2014. https://doi.org/10.1007/s12105-014-0541-9

Brookstone, M. S.; Huvos, A. G. Central salivary gland tumors of the maxilla and mandible: a clinicopathologic study of 11 cases with an analysis of the literature. J Oral Maxillofac Surg, 50: 229-36, 1992. https://doi.org/10.1016/0278-2391(92)90317-S

Coca-Pelaz, A.; Rodrigo, J. P.; Triantafyllou, A.; Hunt, J. L.; Rinaldo, A.; Strojan, P.; Haigentz, M.; Mendenhall, W.; Takes, R.; Vander Poorten, V.; Ferlito, A. Salivary mucoepidermoid carcinoma revisited. Eur Arch Otorhinolaryngol 272, 799–819, 2015. https://doi.org/10.1007/s00405-014-3053-z

Costa, A. L. F.; Ferreira, T. L. D.; Soares, H. A.; NahasScocate, A. C. R.; Montesinos, G. A. P.; and Braz-Silva, P. H. “Cone beam computed tomography diagnostic imaging of intraosseous mucoepidermoid carcinoma in the mandible,” Journal of Clinical and Experimental Dentistry, 1158–61, 2017. https://doi.org/10.4317/jced.53785

El-Naggar, A. K.; Chan, J. K. C.; Grandis, J. R.; Takata, T.; Slootweg, P. J. WHO Classification of Head and Neck Tumors 4th Edition. IARC, 2017.

Eversole, L. R. Mucoepidermoid carcinoma: review of 815 reported cases. Oral Surg Oral Med Oral Pathol, 28:490-5, 1970.

García A. Frecuencia de pacientes con cáncer oral y orofaríngeo atendidos en el Hospital Belén y Hospital Víctor Lazarte Echegaray en la ciudad de Trujillo durante el periodo 2009 – 2015. Tesis de Título Profesional. Universidad Católica Los Ángeles de Chimbote. Trujillo, Perú. 2017.

Holsinger, C.; Owens, J.; Raymond, K.; Myers, J. Central mucoepidermoide carcinoma of the mandible: Tumorigenesis within a keratocyst. Arch Otolaryngol Head Neck Surg, 128:718-20, 2002. https://doi.org/10.1001/archotol.128.6.718

Johnson, B.; & Velez, I. Central Mucoepidermoid Carcinoma With an Atypical Radiographic Appearance Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 106(4): e51-3, 2008. https://doi.org/10.1016/j.tripleo.2008.04.029

Kechagias, N.; Ntomouchtsis, A.; Mavrodi, A.; Christoforidou, B.; Tsekos, A.; & Vahtsevanos, K. Central mucoepidermoid carcinoma of the anterior region of the mandible: report of an unusual case and review of the literature. Oral and Maxillofacial Surgery, 19(3), 309–13, 2015. https://doi.org/10.1007/s10006-015-0483-8

Loos, D. Central mucoepidermoid carcinoma of the jaw. Dtsch Monatschr Zahnheik, 31:308, 1913.

Mejía P. Análisis comparativo del diagnóstico presuntivo y el diagnóstico definitivo en informes anatomopatológicos de pacientes con diagnóstico de cáncer bucal del laboratorio de patología de la clínica estomatológica de la Universidad Peruana Cayetano Heredia, periodos 2016 – 2019. Tesis de Segunda Especialidad. Universidad Peruana Cayetano Heredia. Lima, Perú. 2020.

Nallamilli, S. M.; Tatapudi, R.; Reddy, R. S.; Ravikanth, M.; Rajesh, N. Primary intraosseous mucoepidermoid carcinoma of the maxilla. Ghana Med J, 49(2):120-3, 2015. https://doi.org/10.4314/gmj.v49i2.10

Pindborg, J. J.; Kramer, I. R.; Torloni H. Geneva: World Health O3rganization; Histologic Typing of Odontogenic Tumors, Jaw Cysts and Allied Lesions; 1971.

Rapidis, A. D.; Givalos, N.; Gakiopoulou, H.; Stavrianos, S. D.; Faratzis, G.; Lagogiannis, G. A.; & Patsouris, E. Mucoepidermoid carcinoma of the salivary glands: Review of the literature and clinicopathological analysis of 18 patients. Oral oncology, 43(2):130-6, 2007. https://doi.org/10.1016/j.oraloncology.2006.03.001

Rathore, A. S.; Ahuja, P.; Chhina, S.; Ahuja, A. Primary intraosseous mucoepidermoid carcinoma of maxilla. J Oral Maxillofac Pathol, 18(3):428-31, 2014. https://doi.org/10.4103/0973-029X.151339

Tucci, R.; Matizonkas-Antonio, L. F.; de Carvalhosa, A. A.; Castro, P. H. S.; Nunes, F. D.; & Pinto, D. S., Jr. Central mucoepidermoid carcinoma: report of a case with 11 years evolution and peculiar macroscopical and clinical characteristics. Medicina Oral, Patologia Oral Y Cirugia Bucal, 14(6), E283–6, 2009.

Waldron, C. A.; Mustoe, T. A.; Primary intraosseous carcinoma of the mandible with probable origin in an odontogenic cyst. Oral Surg Oral Med Oral Pathol, 67:716–24, 1989. https://doi.org/10.1016/0030-4220(89)90014-5

Waldron, C. A, Koh M. Central mucoepidermoid carcinoma of the jaws: report of four cases with analysis of the literature and discussion of the relationship to mucoepidermoid, sialodontogenic, and glandular odontogenic cysts. J Oral Maxillofac Surg. 1990;48:871–7. https://doi.org/10.1016/0278-2391(90)90349-7

Published

2021-05-29

Issue

Section

Case Report

Categories

How to Cite

Intraosseous mucoepidermoid carcinoma in mandible: Case report and literature review. (2021). Odontología Vital, 1(34), 78-85. https://doi.org/10.59334/ROV.v1i34.429

Similar Articles

1-10 of 205

You may also start an advanced similarity search for this article.