Changes in salivary composition of chemically dependent subjects

Authors

  • Luciana Lyra Universidade Federal do Paraná
  • William Bellani Universidade Federal do Paraná
  • Carolina E. Mazur Universidade Federal do Paraná
  • João A. Brancher Pontifícia Universidade Católica do Paraná
  • Antonio Adilson S. de Lima, Universidade Federal do Paraná
  • José Miguel Amenábar Universidade Federal do Paraná

DOI:

https://doi.org/10.59334/ROV.v1i32.381

Keywords:

Saliva, alcohol, cannabis, cocaine, salivary composition, substance-related disorders, substance dependence, drugs

Abstract

Chemically dependent subjects may present relevant changes in the volume and composition of salivary fluid
because the secretion of the salivary glands is controlled by the parasympathetic and sympathetic system. The
aim of this study was to compare the salivary concentration of total proteins, amylase, urea, calcium, phosphate
and flow rate between chemically dependent and non-chemically dependent subjects. Saliva flow rate, calcium,
phosphate, total protein, amylase and urea concentrations were measure in both groups: chemical dependent
group (n=27) and control group (n=27). Saliva samples, from the chemically dependents, were taken one day
before the beginning of the detoxification treatment. Statistical analysis was undertaken using t-test. The
salivary flow and the urea concentration did not present statistically significant difference between the groups.
However, total proteins, amylase, calcium and phosphate concentrations were statistically higher on the chemical
dependents group. Saliva composition seems to be modified by the chronic use of alcohol and illicit drugs

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Published

2020-10-06

How to Cite

Lyra, L. ., Bellani, W. ., Mazur, C. E., Brancher, J. A., de Lima, , A. A. S. ., & Amenábar, J. M. . (2020). Changes in salivary composition of chemically dependent subjects. O.V., 1(32). https://doi.org/10.59334/ROV.v1i32.381

Issue

Section

Research Article

Métricas alternativas